Uterine Fibroids
Conditions & Life Stages · Reviewed August 2026
Definition
Uterine fibroids, also called leiomyomas, are common benign growths of smooth muscle and fibrous tissue that develop in or on the wall of the uterus.[1] They're extremely common, with cumulative incidence by age 50 estimated above 80% in Black women and near 70% in white women, and many people who have them never notice a symptom.[3]
Educational content, not medical advice. For personal or fertility concerns, please consult your doctor.
What Uterine Fibroids Are
Researchers describe fibroids as benign tumors made of smooth muscle cells and fibroblasts, held together by a substantial amount of fibrous extracellular matrix.[2] A fibroid grows from a single cell line that starts dividing out of control, which is why the medical literature calls it a monoclonal, or clonal, growth.[1] Fibroids vary enormously in size, number, and location within the uterus, and that variation is a big part of why they're described as heterogeneous, ranging from tiny growths that never cause a symptom to large ones tied to substantial bleeding and pain.[2]
How Common They Are
Fibroids are the most common benign tumor of the reproductive tract.[1] A widely cited study of 1,364 women aged 35 to 49 used ultrasound screening for premenopausal participants, rather than relying on which women reported symptoms, and found the cumulative incidence by age 50 was more than 80% among Black women and nearly 70% among white women.[3] That racial gap tracks with a broader pattern in the research: Black women tend to develop fibroids earlier in life and to develop more severe forms of the disease.[2]
What People With Fibroids Commonly Track
The literature ties fibroids to abnormal uterine bleeding, heavy menstrual bleeding, pelvic pain and pressure, and bladder or bowel symptoms, with which symptoms show up depending heavily on a fibroid's size and location.[1] Fibroids that sit just under the uterine lining, called submucosal fibroids, are more likely to disrupt normal bleeding and can cause heavy bleeding even when small. Larger fibroids that bulge outward are more likely to press on nearby organs instead, with fibroids toward the front of the uterus more often tied to pelvic pressure and bladder symptoms and fibroids toward the back more often tied to constipation.[1]
Because of that bleeding link, people navigating a fibroid diagnosis often keep a day-by-day record of heavy menstrual bleeding and period flow, alongside cramps and where pelvic pain shows up across the cycle rather than just on period days. Heavy, recurring blood loss also affects iron status: a 2026 claims-based study that compared large matched cohorts of women found anemia developed in about a third of those with both fibroids and heavy menstrual bleeding, compared with 4.4% of women with neither.[4] That's the mechanism that makes flow logs worth reading alongside a lab result like ferritin.
How Go Go Gaia Supports Tracking It
Go Go Gaia logs period flow, cramps, and pelvic pain each with their own 1-click entry, timestamped and charted against your cycle day. If you upload lab results like ferritin, the app charts those values on the same timeline, so a heavy-flow stretch and a lab draw show up side by side instead of living in separate places.
Track flow, pain, and your labs in one place
Log period flow, cramps, and pelvic pain alongside any lab results you upload, like ferritin, in Go Go Gaia.
Download on the App StoreFree to log. No account needed to start.
What the Research Shows
Screening-based research puts the lifetime chance of developing a fibroid well above what symptom-based counts alone would suggest. In the ultrasound-based cohort described above, cumulative incidence by age 50 reached more than 80% for Black women and nearly 70% for white women, regardless of whether those women had ever reported a symptom.[3]
Fibroids account for one-third to half of all hysterectomies performed in the United States, and roughly three-quarters of fibroid treatments are hysterectomies, a measure of how much of the disease's burden comes from its more symptomatic cases.[2]
A 2026 study using insurance claims data compared three matched cohorts of 22,057 women each and found anemia developed in about a third of women with both fibroids and heavy menstrual bleeding, compared with 4.4% of the comparison group with neither. Women who developed anemia went on to have substantially higher rates of hysterectomy and blood transfusion than those who didn't.[4]
Related Terms
Heavy Menstrual Bleeding
Flow logged by amount or product changes, one of the symptoms most consistently tied to fibroids in the research above.
Cramps (Dysmenorrhea)
Crampy pain that follows the start of a period, often logged alongside flow and pelvic pain.
Pelvic Pain
Discomfort in the lower abdomen or pelvis that can occur on any cycle day, not just during a period.
Period Flow
The day-by-day record of menstrual bleeding that pairs with cramps and pelvic pain entries.
Ferritin
The iron-storage marker population research ties to heavy, recurring menstrual blood loss.
Frequently Asked Questions
Educational information based on published sources. Not medical advice. For personal concerns, please consult your doctor.
How common are uterine fibroids?
Very common. A widely cited study of 1,364 women aged 35 to 49, which used ultrasound screening for premenopausal participants rather than relying on reported symptoms, found the cumulative incidence by age 50 was more than 80% among Black women and nearly 70% among white women.[3]
Do all uterine fibroids cause symptoms?
No. Fibroids vary enormously in size, number, and location, and researchers describe their clinical presentation as ranging from no symptoms at all to substantial bleeding and pain. When symptoms occur, they're most often abnormal or heavy bleeding, pelvic pain and pressure, and bladder or bowel symptoms tied to where a fibroid sits.[1][2]
Why do people with fibroids track iron-related labs like ferritin?
Heavy, recurring blood loss affects iron status. A 2026 claims-based study found anemia developed in about a third of women who had both fibroids and heavy menstrual bleeding, compared with 4.4% of women with neither, which is why flow logs and iron-panel results are often read together.[4]
References
- Rezk A, Kahn J, Singh M. Fertility Sparing Management in Uterine Fibroids. StatPearls [Internet]. NCBI Bookshelf. NBK574504
- Stewart EA, Laughlin-Tommaso SK, Catherino WH, Lalitkumar S, Gupta D, Vollenhoven B. Uterine fibroids. Nature Reviews Disease Primers. 2016;2:16043. doi.org/10.1038/nrdp.2016.43
- Baird DD, Dunson DB, Hill MC, Cousins D, Schectman JM. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. American Journal of Obstetrics and Gynecology. 2003;188(1):100-107. doi.org/10.1067/mob.2003.99
- McKain L, Brady BL, Tran AT, Lickert C. Burden of anemia in women with uterine fibroid-associated heavy menstrual bleeding. AJOG Global Reports. 2026;6(3):100652. doi.org/10.1016/j.xagr.2026.100652
Sourced from peer-reviewed research and, for basic mechanism claims, established references like NIH and StatPearls. Every citation above is checked to confirm it resolves to a real source and supports the sentence it's attached to. Last reviewed August 2026. See our full methodology on the Encyclopedia hub.